SCHEMBL8772404

SCHEMBL8772404

CCCCCCc1cc(Cc2ccccc2)c(C)cc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.49
ALOX5 P09917 2/20 0.49
MEN1 O00255 1/20 0.49
TP53 P04637 1/20 0.49
CYP3A4 P08684 1/20 0.49
MAPT P10636 1/20 0.49
ALOX15 P16050 1/20 0.49
TSHR P16473 1/20 0.49
HTT P42858 1/20 0.49
KMT2A Q03164 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
CNR1 P21554 2/20 0.48
CNR2 P34972 2/20 0.48
LDHA P00338 1/20 0.46
LDHB P07195 1/20 0.46
BCL2L1 Q07817 3/20 0.45
BCL2 P10415 1/20 0.45
BID P55957 3/20 0.43
MCL1 Q07820 3/20 0.43
BAK1 Q16611 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27688364 0.83 BCL2 (0.52) TYRALOX5MEN1TP53CYP3A4
SCHEMBL2775231 0.83 ALOX5 (0.58) TYRALOX5MEN1TP53CYP3A4
SCHEMBL11681338 0.82 BCL2 (0.59) TYRALOX5MEN1TP53CYP3A4
SCHEMBL27544190 0.81 ALOX5 (0.56) TYRALOX5MEN1TP53CYP3A4
SCHEMBL15313677 0.81 CNR1 (0.48) TYRALOX5MEN1TP53CYP3A4
SCHEMBL11683205 0.80 BCL2 (0.56) TYRALOX5MEN1TP53CYP3A4
SCHEMBL10988396 0.79 BID (0.55) TYRALOX5MEN1TP53CYP3A4
SCHEMBL22054607 0.78 BCL2 (0.73) ALOX5MEN1CYP3A4ALOX15TSHR
SCHEMBL28233540 0.78 TYR (0.53) TYRALOX5MEN1TP53CYP3A4
SCHEMBL11331296 0.77 BID (0.52) MAPTALOX15CNR1CNR2BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed