Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10721366 | 0.92 | ABCB1 (0.64) | ABCB1CYP3A4CYP2C9POLB | |
| SCHEMBL9714534 | 0.87 | POLB (0.67) | ABCB1CYP3A4CYP2C9POLB | |
| SCHEMBL9714333 | 0.86 | ABCB1 (0.55) | ABCB1CYP3A4CYP2C9POLB | |
| SCHEMBL10721508 | 0.82 | ABCB1 (0.77) | ABCB1CYP3A4CYP2C9POLB | |
| SCHEMBL8461192 | 0.82 | ABCB1 (0.81) | ABCB1CYP3A4 | |
| SCHEMBL10721301 | 0.82 | ABCB1 (0.77) | ABCB1CYP3A4CYP2C9POLB | |
| SCHEMBL17624858 | 0.82 | ABCB1 (0.77) | ABCB1 | |
| SCHEMBL32672049 | 0.82 | ABCB1 (0.81) | ABCB1CYP3A4 | |
| SCHEMBL678529 | 0.82 | ABCB1 (0.70) | ABCB1CYP3A4 | |
| SCHEMBL5064009 | 0.81 | ABCB1 (0.73) | ABCB1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639559-B1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM & HAAS (US) | 1997-10-15 | — | — | EP | claimed |
| EP-0639559-A1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM AND HAAS COMPANY (US) | 1995-02-22 | — | — | EP | claimed |
| EP-0639559-B1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM & HAAS (US) | 1997-10-15 | — | — | EP | disclosed |