Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.45 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.43 |
| ▸ | RHOC | P08134 | 1/20 | 0.43 |
| ▸ | RHOA | P61586 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476394 | 1.00 | ABL1 (0.60) | ABL1SMN1; SMN2LMNAKCNH3PNLIP | |
| SCHEMBL11337552 | 1.00 | ABL1 (0.60) | ABL1SMN1; SMN2LMNAKCNH3PNLIP | |
| SCHEMBL27371937 | 1.00 | ABL1 (0.60) | ABL1SMN1; SMN2LMNAKCNH3PNLIP | |
| SCHEMBL11340617 | 1.00 | ABL1 (0.60) | ABL1SMN1; SMN2LMNAKCNH3PNLIP | |
| SCHEMBL11339627 | 1.00 | ABL1 (0.60) | ABL1SMN1; SMN2LMNAKCNH3PNLIP | |
| SCHEMBL11322768 | 1.00 | ABL1 (0.60) | ABL1SMN1; SMN2LMNAKCNH3PNLIP | |
| SCHEMBL11337429 | 1.00 | ABL1 (0.60) | ABL1SMN1; SMN2LMNAKCNH3PNLIP | |
| SCHEMBL9730868 | 0.98 | ABL1 (0.57) | ABL1SMN1; SMN2LMNAKCNH3PNLIP | |
| SCHEMBL7793228 | 0.92 | SMN1; SMN2 (0.56) | ABL1SMN1; SMN2LMNACNR1RHOC | |
| Sulfuric Acid SCHEMBL28460959 | 0.91 | ABL1 (0.53) | ABL1SMN1; SMN2LMNAPNLIPCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109836365-B | Amine thioacyl fluoride derivatives and synthetic method thereof | 华东师范大学 | 2021-02-26 | — | — | CN | disclosed |
| CN-103833561-B | The N-arylation method of alkane amine | HENGYANG NORMAL UNIVERSITY (CN) | 2016-01-13 | — | — | CN | disclosed |
| CN-103833561-A | Method for N-arylation of alkane amine | UNIV HENGYANG NORMAL | 2014-06-04 | — | — | CN | disclosed |
| CN-101402537-B | Uses of 2-pyridine-beta ketone compounds | GUANGZHOU INST BIOMED & HEALTH | 2011-04-27 | — | — | CN | disclosed |
| CN-101402537-A | Uses of 2-pyridine-beta ketone compounds | GUANGZHOU INST BIOMED & HEALTH (CN) | 2009-04-08 | — | — | CN | disclosed |
| CN-1175246-A | Substituted azetidin-2-ones for treatment of atherosclerosis | SMITHKLINE BEECHAM PLC (GB) | 1998-03-04 | — | — | CN | disclosed |
| EP-0799200-A1 | SUBSTITUTED AZETIDIN-2-ONES FOR TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | disclosed |
| EP-0002721-B1 | PROCESS FOR PREPARING HYDRAZINES | BAYER AG (DE) | 1981-09-02 | — | — | EP | disclosed |
| EP-0002721-A2 | Process for preparing hydrazines | BAYER AG (DE) | 1979-07-11 | — | — | EP | disclosed |