SCHEMBL9730868

SCHEMBL9730868

CCCCCNc1ccc(Cl)cc1

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.56
LMNA P02545 1/20 0.50
KCNH3 Q9ULD8 2/20 0.46
RHOC P08134 1/20 0.44
RHOA P61586 1/20 0.44
NR1I2 O75469 1/20 0.44
AHR P35869 1/20 0.44
TNIK Q9UKE5 1/20 0.43
CNR1 P21554 2/20 0.43
PNLIP P16233 1/20 0.43
HDAC3 O15379 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC2 Q92769 1/20 0.42
CNR2 P34972 1/20 0.42
POLB P06746 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11322768 0.98 ABL1 (0.60) ABL1SMN1; SMN2LMNAKCNH3RHOC
SCHEMBL11337552 0.98 ABL1 (0.60) ABL1SMN1; SMN2LMNAKCNH3RHOC
SCHEMBL27371937 0.98 ABL1 (0.60) ABL1SMN1; SMN2LMNAKCNH3RHOC
SCHEMBL11337429 0.98 ABL1 (0.60) ABL1SMN1; SMN2LMNAKCNH3RHOC
SCHEMBL11339627 0.98 ABL1 (0.60) ABL1SMN1; SMN2LMNAKCNH3RHOC
SCHEMBL11340617 0.98 ABL1 (0.60) ABL1SMN1; SMN2LMNAKCNH3RHOC
SCHEMBL3476394 0.98 ABL1 (0.60) ABL1SMN1; SMN2LMNAKCNH3RHOC
SCHEMBL8772460 0.98 ABL1 (0.60) ABL1SMN1; SMN2LMNAKCNH3RHOC
SCHEMBL7793228 0.94 SMN1; SMN2 (0.56) ABL1SMN1; SMN2LMNARHOCRHOA
Sulfuric Acid SCHEMBL28460959 0.89 ABL1 (0.53) ABL1SMN1; SMN2LMNACNR1PNLIP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5116982-A Fluorination DOWELANCO (US) 1992-05-26 US claimed
CN-111019025-B High-purity polypropylene polymerization method 北方华锦化学工业股份有限公司 2022-05-17 CN disclosed
CN-111019025-A High-purity polypropylene polymerization method 北方华锦化学工业股份有限公司 2020-04-17 CN disclosed
CN-100497345-C 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis OTSUKA PHARMA CO LTD (JP) 2009-06-10 CN disclosed
CN-1878777-A 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis OTSUKA PHARMA CO LTD (JP) 2006-12-13 CN disclosed
EP-0002721-B1 PROCESS FOR PREPARING HYDRAZINES BAYER AG (DE) 1981-09-02 EP disclosed
EP-0002721-A2 Process for preparing hydrazines BAYER AG (DE) 1979-07-11 EP disclosed