Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | TACR2 | P21452 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5429778 | 0.88 | CYP2A6 (0.50) | HSD17B10LMNATYRALDH1A1CYP2A6 | |
| SCHEMBL1919 | 0.85 | — | — | |
| SCHEMBL31544783 | 0.83 | HSD17B10 (0.94) | HSD17B10LMNAMAOBTYRALDH1A1 | |
| SCHEMBL28981622 | 0.83 | HSD17B10 (0.94) | HSD17B10LMNAMAOBTYRALDH1A1 | |
| SCHEMBL8995751 | 0.83 | HSD17B10 (0.94) | HSD17B10LMNAMAOBTYRALDH1A1 | |
| Hydrochloric Acid SCHEMBL5255687 | 0.83 | HSD17B10 (0.94) | HSD17B10LMNAMAOBTYRALDH1A1 | |
| SCHEMBL4391231 | 0.83 | HSD17B10 (0.67) | HSD17B10TACR2DAOLMNAMAOB | |
| SCHEMBL1283575 | 0.82 | ALDH1A1 (0.57) | HSD17B10TAAR1LMNAMAOBALDH1A1 | |
| SCHEMBL9373207 | 0.82 | HSD17B10 (0.53) | HSD17B10MAOBALDH1A1IDO1 | |
| SCHEMBL14330452 | 0.81 | CYP2A6 (0.44) | HSD17B10LMNATYRALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639559-B1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM & HAAS (US) | 1997-10-15 | — | — | EP | claimed |