Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772539 | 0.85 | NQO2 (0.41) | KDM4EALDH1A1HSD17B10CYP1A2CYP2C19 | |
| SCHEMBL8405592 | 0.74 | ADRA2A (0.46) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL13902883 | 0.74 | ADRA2A (0.46) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL97610 | 0.73 | KDM4E (0.45) | KDM4EHTTMTNR1AITGB2ICAM1 | |
| SCHEMBL3273390 | 0.72 | KCNJ1 (0.45) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL668947 | 0.71 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL23870266 | 0.71 | ADRA2A (0.44) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL16066059 | 0.71 | ADRA2A (0.44) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL7473749 | 0.71 | ADRA2A (0.44) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL8405587 | 0.70 | ADRA2A (0.38) | KDM4EALDH1A1HPGDHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639559-B1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM & HAAS (US) | 1997-10-15 | — | — | EP | claimed |