Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29400785 | 0.88 | SMN1; SMN2 (0.63) | SMN1; SMN2CYP2C19RAB9ANPC1KMT2A | |
| SCHEMBL29677774 | 0.88 | SMN1; SMN2 (0.63) | SMN1; SMN2CYP2C19RAB9ANPC1KMT2A | |
| SCHEMBL119502 | 0.88 | SMN1; SMN2 (0.63) | SMN1; SMN2CYP2C19RAB9ANPC1KMT2A | |
| SCHEMBL8361479 | 0.87 | L3MBTL1 (0.48) | SMN1; SMN2CYP2C19GAARAB9ANPC1 | |
| SCHEMBL874549 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19GAARAB9ANPC1 | |
| SCHEMBL27841040 | 0.86 | KMT2A (0.48) | SMN1; SMN2CYP2C19GAARAB9ANPC1 | |
| SCHEMBL13327274 | 0.86 | POLB (0.52) | SMN1; SMN2GAAKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL22397770 | 0.86 | POLB (0.52) | SMN1; SMN2GAAKMT2AL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2298842 | 0.85 | KMT2A (0.47) | SMN1; SMN2CYP2C19GAARAB9ANPC1 | |
| SCHEMBL693889 | 0.85 | L3MBTL1 (0.48) | SMN1; SMN2CYP2C19GAARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801083-A2 | Improved functionalized resin for chemical synthesis | PFIZER INC. (US) | 1997-10-15 | — | — | EP | disclosed |