Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439456 | 0.89 | KDM4E (0.40) | ALDH1A1KDM4ETDP1KMT2AMEN1 | |
| SCHEMBL8443653 | 0.89 | KMT2A (0.46) | ALDH1A1KDM4ETDP1LMNAKMT2A | |
| SCHEMBL8108487 | 0.85 | TSHR (0.43) | ALDH1A1KDM4ETDP1LMNASMN1; SMN2 | |
| SCHEMBL8443006 | 0.84 | POLB (0.41) | ALDH1A1KDM4ETDP1LMNAPOLB | |
| SCHEMBL8441254 | 0.83 | MEN1 (0.39) | ALDH1A1KDM4ETDP1LMNASMN1; SMN2 | |
| SCHEMBL8772503 | 0.83 | TRPV1 (0.48) | ALDH1A1LMNAKMT2ATSHRNAMPT | |
| SCHEMBL27495125 | 0.83 | TRPV1 (0.48) | ALDH1A1LMNAKMT2ATSHRNAMPT | |
| SCHEMBL8438732 | 0.83 | TRPV1 (0.48) | ALDH1A1LMNAKMT2ATSHRNAMPT | |
| SCHEMBL27515042 | 0.83 | TRPV1 (0.48) | ALDH1A1LMNAKMT2ATSHRNAMPT | |
| SCHEMBL8442084 | 0.83 | TRPV1 (0.48) | ALDH1A1LMNAKMT2ATSHRNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799200-A1 | SUBSTITUTED AZETIDIN-2-ONES FOR TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | claimed |