Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772635 | 0.99 | FDFT1 (0.46) | FDFT1MMP13L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL8772588 | 0.88 | PTGDR (0.39) | FDFT1MMP13ALDH1A1LMNAKMT2A | |
| SCHEMBL8772687 | 0.88 | FDFT1 (0.37) | FDFT1L3MBTL1MAPK1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL8772602 | 0.88 | FDFT1 (0.42) | FDFT1L3MBTL1ALDH1A1LMNAKMT2A | |
| SCHEMBL8772637 | 0.87 | FDFT1 (0.38) | FDFT1L3MBTL1MAPK1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL8772650 | 0.86 | FDFT1 (0.37) | FDFT1L3MBTL1MAPK1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL8772550 | 0.86 | MMP13 (0.45) | FDFT1MMP13MAPK1ALDH1A1LMNA | |
| SCHEMBL8420308 | 0.84 | FDFT1 (0.65) | FDFT1L3MBTL1MAPK1ALDH1A1LMNA | |
| SCHEMBL8772672 | 0.82 | MMP13 (0.44) | FDFT1MMP13MAPK1ALDH1A1LMNA | |
| SCHEMBL8592554 | 0.82 | MMP13 (0.44) | FDFT1MMP13MAPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691349-A | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 1997-11-25 | — | — | US | disclosed |
| EP-0654032-B1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LTD (GB) | 1997-10-15 | — | — | EP | disclosed |
| EP-0654032-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS. | ZENECA LTD (GB) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994003451-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-02-17 | — | — | WO | disclosed |