Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 12/20 | 0.39 |
| ▸ | RARB | P10826 | 9/20 | 0.39 |
| ▸ | RXRA | P19793 | 6/20 | 0.39 |
| ▸ | RARA | P10276 | 8/20 | 0.35 |
| ▸ | RXRB | P28702 | 3/20 | 0.32 |
| ▸ | RXRG | P48443 | 3/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772694 | 0.87 | RARG (0.42) | RARGRARBRXRARARARXRB | |
| SCHEMBL8562392 | 0.81 | RARB (0.42) | RARGRARBRXRARARAP2RX7 | |
| SCHEMBL8772664 | 0.76 | RARB (0.40) | RARGRARBRXRARARA | |
| SCHEMBL8772662 | 0.74 | RARB (0.42) | RARGRARBRXRARARA | |
| SCHEMBL8772826 | 0.72 | RARB (0.39) | RARGRARBRXRARARALTB4R2 | |
| SCHEMBL8772592 | 0.72 | CYP26A1 (0.30) | RARGRARBRARA | |
| SCHEMBL8772752 | 0.72 | RARB (0.36) | RARGRARBRXRARARA | |
| SCHEMBL8772736 | 0.72 | RARB (0.38) | RARGRARBRXRARARA | |
| SCHEMBL8660641 | 0.71 | RARB (0.36) | RARGRARBRXRARARALTB4R2 | |
| SCHEMBL8836702 | 0.70 | RARB (0.60) | RARGRARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800517-A1 | ACETYLENES DISUBSTITUTED WITH A 5 OR 8 SUBSTITUTED TETRAHYDRONAPHTHYL OR DIHYDRONAPHTHYL GROUP AND WITH AN ARYL OR HETEROARYL GROUPS HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | Allergan (US) | 1997-10-15 | — | — | EP | disclosed |