Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.36 |
| ▸ | RARG | P13631 | 7/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 7/20 | 0.34 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 2/20 | 0.31 |
| ▸ | F7 | P08709 | 2/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648772 | 0.92 | RARB (0.36) | RARBRARGRXRARARAPTPN22 | |
| SCHEMBL8772694 | 0.74 | RARG (0.42) | RARBRARGRXRARARA | |
| SCHEMBL8772664 | 0.74 | RARB (0.40) | RARBRARGRXRARARA | |
| SCHEMBL8633713 | 0.73 | RARB (0.33) | RARBRARGRXRARARA | |
| SCHEMBL8562392 | 0.72 | RARB (0.42) | RARBRARGRXRARARALTB4R2 | |
| SCHEMBL8772662 | 0.72 | RARB (0.42) | RARBRARGRXRARARA | |
| SCHEMBL8772633 | 0.71 | RARB (0.47) | RARBRARGRXRARARA | |
| SCHEMBL8772676 | 0.71 | RARG (0.39) | RARBRARGRXRARARALTB4R2 | |
| SCHEMBL8772826 | 0.71 | RARB (0.39) | RARBRARGRXRARARALTB4R2 | |
| SCHEMBL8651566 | 0.71 | RARB (0.33) | RARBRARGRXRARARALTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825986-A1 | QUINOLYL-ETHYNYL DERIVATIVES HAVING RETINOID-LIKE ACTIVITY | Allergan (US) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996036609-A1 | QUINOLYL-ETHYNYL DERIVATIVES HAVING RETINOID-LIKE ACTIVITY | ALLERGAN (US) | 1996-11-21 | — | — | WO | disclosed |