Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.63 |
| ▸ | MMP13 | P45452 | 16/20 | 0.54 |
| ▸ | MMP2 | P08253 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969941 | 0.86 | FDFT1 (0.61) | FDFT1MMP13MMP2 | |
| SCHEMBL8772564 | 0.85 | MMP13 (0.61) | FDFT1MMP13MMP2 | |
| Hydrochloric Acid SCHEMBL8772652 | 0.83 | MMP13 (0.62) | FDFT1MMP13MMP2 | |
| SCHEMBL8772597 | 0.79 | MMP13 (0.58) | FDFT1MMP13MMP2 | |
| SCHEMBL8648805 | 0.77 | FDFT1 (0.53) | FDFT1MMP13MMP2 | |
| SCHEMBL8973148 | 0.76 | FDFT1 (0.60) | FDFT1MMP13MMP2 | |
| SCHEMBL8772636 | 0.74 | MMP13 (0.90) | FDFT1MMP13MMP2 | |
| SCHEMBL8592665 | 0.70 | MMP13 (0.53) | FDFT1MMP13MMP2 | |
| SCHEMBL9328232 | 0.69 | HSD17B10 (0.61) | — | |
| SCHEMBL8433963 | 0.69 | HSD17B10 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0654032-B1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LTD (GB) | 1997-10-15 | — | — | EP | claimed |
| EP-0654032-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS. | ZENECA LTD (GB) | 1995-05-24 | — | — | EP | claimed |
| WO-1994003451-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-02-17 | — | — | WO | claimed |
| EP-0654032-B1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LTD (GB) | 1997-10-15 | — | — | EP | disclosed |
| EP-0654032-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS. | ZENECA LTD (GB) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994003451-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-02-17 | — | — | WO | disclosed |