SCHEMBL8772877

SCHEMBL8772877

CCCCCCCC/C=C\CCCCCCCC(=O)NC(C)NC(=O)CCCCCCC/C=C\CCCCCCCC

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.66
ASAH2 Q9NR71 1/20 0.66
MEN1 O00255 1/20 0.62
MAPK1 P28482 1/20 0.62
KMT2A Q03164 1/20 0.62
LPAR3 Q9UBY5 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.61
KCNK3 O14649 1/20 0.61
ALDH1A1 P00352 1/20 0.61
THRB P10828 1/20 0.61
CNR2 P34972 1/20 0.61
BLM P54132 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
SLC6A5 Q9Y345 1/20 0.61
DEGS1 O15121 1/20 0.61
CETP P11597 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1456866 0.90 FAAH (0.79) FAAHASAH2MEN1MAPK1KMT2A
SCHEMBL6903752 0.90 FAAH (0.79) FAAHASAH2MEN1MAPK1KMT2A
SCHEMBL1456449 0.90 FAAH (0.79) FAAHASAH2MEN1MAPK1KMT2A
SCHEMBL11075676 0.89 ASAH2 (0.62) FAAHASAH2MEN1KMT2ALPAR3
SCHEMBL2146114 0.89 FAAH (0.77) FAAHASAH2MEN1MAPK1KMT2A
SCHEMBL9109309 0.88 ASAH2 (0.68) FAAHASAH2MEN1MAPK1KMT2A
SCHEMBL6846748 0.88 ASAH2 (0.68) FAAHASAH2MEN1MAPK1KMT2A
SCHEMBL1147692 0.88 ASAH2 (0.68) FAAHASAH2MEN1MAPK1KMT2A
SCHEMBL2225404 0.88 ASAH2 (0.68) FAAHASAH2MEN1MAPK1KMT2A
SCHEMBL3280569 0.88 FAAH (0.60) FAAHASAH2MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0614622-B1 Pressure-compensating compositions and pads made therefrom RIK MEDICAL L L C (US) 1997-08-27 EP disclosed
EP-0614622-A1 Pressure-compensating compositions and pads made therefrom JAY MEDICAL, LTD. (US) 1994-09-14 EP disclosed