SCHEMBL8772987

SCHEMBL8772987

Nc1ccc([N+](=O)[O-])c(-c2ccccc2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.61
ALDH1A1 P00352 4/20 0.61
TSHR P16473 2/20 0.56
CYP3A4 P08684 2/20 0.52
ALOX15 P16050 2/20 0.52
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
PSMD14 O00487 1/20 0.50
PRKACA P17612 1/20 0.50
CASP6 P55212 1/20 0.50
MAPK1 P28482 2/20 0.49
RECQL P46063 1/20 0.49
HSD17B10 Q99714 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
CRHBP P24387 1/20 0.47
CRHR2 Q13324 1/20 0.47
CYP19A1 P11511 1/20 0.45
PTGDR2 Q9Y5Y4 1/20 0.43
POLB P06746 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31349171 0.86 ALDH1A1 (0.61) TDP1ALDH1A1TSHRCYP3A4ALOX15
SCHEMBL6404321 0.86 ALDH1A1 (0.61) TDP1ALDH1A1TSHRCYP3A4ALOX15
SCHEMBL2332563 0.84 TDP1 (0.47) TDP1ALDH1A1TSHRCYP3A4ALOX15
SCHEMBL17742439 0.81 TDP1 (0.66) TDP1ALDH1A1CYP3A4MEN1KMT2A
SCHEMBL2327167 0.81 NPC1 (0.45) TDP1ALDH1A1TSHRMEN1KMT2A
SCHEMBL15461976 0.81 ALDH1A1 (0.69) TDP1ALDH1A1TSHRCYP3A4MEN1
SCHEMBL10713235 0.80 TDP1 (0.58) TDP1ALDH1A1TSHRCYP3A4ALOX15
SCHEMBL10904251 0.80 ALDH1A1 (0.63) TDP1ALDH1A1TSHRMAPK1CRHBP
SCHEMBL22007056 0.79 ALDH1A1 (0.67) TDP1ALDH1A1TSHRCYP3A4MEN1
SCHEMBL11792031 0.79 ALDH1A1 (0.88) TDP1ALDH1A1TSHRCYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117247515-A Polyimide containing Trringer's Base element and gas separation membrane and method prepared by polyimide 西北工业大学 2023-12-19 CN claimed
CN-116854913-A Preparation method of high-impact-resistance bismaleimide resin 西北工业大学 2023-10-10 CN claimed
US-12559455-B2 Compound as a UBR box domain ligand AUTOTAC INC. (KR) 2026-02-24 US disclosed
CN-117247515-A Polyimide containing Trringer's Base element and gas separation membrane and method prepared by polyimide 西北工业大学 2023-12-19 CN disclosed
CN-116854913-A Preparation method of high-impact-resistance bismaleimide resin 西北工业大学 2023-10-10 CN disclosed
CN-116375760-A Diamine containing DDSQ element and polyimide gas separation membrane prepared from diamine and method 西北工业大学 2023-07-04 CN disclosed
US-20230174470-A1 COMPOUND AS A UBR BOX DOMAIN LIGAND AUTOTAC INC. (KR) 2023-06-08 US disclosed
US-20230174470-A1 COMPOUND AS A UBR BOX DOMAIN LIGAND AUTOTAC INC. (KR) 2023-06-08 US disclosed
WO-2023074936-A1 BIFUNCTIONAL COMPOUND USING UBR BOX DOMAIN-BINDING LIGAND 주식회사 오토텍바이오 2023-05-04 WO disclosed
EP-4144722-A1 COMPOUND AS UBR BOX DOMAIN LIGAND Autotac Inc. (KR) 2023-03-08 EP disclosed
EP-0635483-B1 Process for preparing nitroaniline derivatives SUMITOMO CHEMICAL CO (JP) 1997-10-22 EP disclosed
US-5466871-A Amination of a nitrobenzene with a hydroxylamine SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-11-14 US disclosed
EP-0635483-A1 Process for preparing nitroaniline derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174470-A1 COMPOUND AS A UBR BOX DOMAIN LIGAND UBR4, UBQLN2, UBTF TDP1 3622/4885ALDH1A1 2317/4885TSHR 2205/4885
US-12559455-B2 Compound as a UBR box domain ligand UBR4, UBTF, UBQLN1 TDP1 3804/4885ALDH1A1 1486/4885TSHR 1240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.