Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792626 | 0.94 | TSHR (0.48) | TSHRALDH1A1TDP1CYP3A4KDM4E | |
| SCHEMBL1497989 | 0.90 | TSHR (0.60) | TSHRALDH1A1TDP1ALOX15CYP3A4 | |
| SCHEMBL27771692 | 0.88 | TSHR (0.58) | TSHRALDH1A1TDP1ALOX15CYP3A4 | |
| SCHEMBL28171346 | 0.88 | TSHR (0.58) | TSHRALDH1A1TDP1ALOX15CYP3A4 | |
| SCHEMBL30490414 | 0.88 | TSHR (0.58) | TSHRALDH1A1TDP1ALOX15CYP3A4 | |
| Ethylene SCHEMBL29290025 | 0.86 | TSHR (0.56) | TSHRALDH1A1TDP1ALOX15CYP3A4 | |
| SCHEMBL3295168 | 0.83 | TSHR (0.43) | TSHRALDH1A1TDP1ALOX15CYP3A4 | |
| SCHEMBL30682787 | 0.83 | TSHR (0.43) | TSHRALDH1A1TDP1ALOX15CYP3A4 | |
| SCHEMBL366798 | 0.83 | GPR35 (0.56) | TSHRALDH1A1TDP1CYP3A4KDM4E | |
| Ethylene Glycol SCHEMBL29290024 | 0.82 | TSHR (0.53) | TSHRALDH1A1TDP1ALOX15CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981925-B2 | Substituted benzo[d][1,2,3]triazines as p70S6K inhibitors | MERCK PATENT GMBH (DE) | 2018-05-29 | — | — | US | disclosed |
| US-20160340323-A1 | AZAQUINAZOLINE CARBOXAMIDE DERIVATIVES | MERCK PATENT GMBH (DE) | 2016-11-24 | — | — | US | disclosed |
| US-20160340323-A1 | AZAQUINAZOLINE CARBOXAMIDE DERIVATIVES | MERCK PATENT GMBH (DE) | 2016-11-24 | — | — | US | disclosed |
| EP-0791004-A1 | ACYLATED BENZYLGLYCOSIDES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996014325-A1 | ACYLATED BENZYLGLYCOSIDES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160340323-A1 | AZAQUINAZOLINE CARBOXAMIDE DERIVATIVES | RPS6KA3, RPS6KA4, CDK4 | TSHR 2532/4885ALDH1A1 3527/4885TDP1 2354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.