Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773188 | 0.87 | MAOB (0.51) | LOXLOXL2CHRM5ALDH1A1CETP | |
| SCHEMBL7108244 | 0.86 | MAPT (0.48) | LOXL2CHRM5F10KDM4EALDH1A1 | |
| SCHEMBL8773194 | 0.84 | CHRM5 (0.42) | LOXLOXL2CHRM5L3MBTL1LMNA | |
| SCHEMBL7108315 | 0.84 | CTSS (0.41) | CHRM5L3MBTL1F10KDM4EMEN1 | |
| SCHEMBL8074651 | 0.83 | MAPT (0.57) | LOXLOXL2L3MBTL1F10MAPT | |
| SCHEMBL8509396 | 0.82 | F10 (0.47) | LOXLOXL2CHRM5L3MBTL1F10 | |
| SCHEMBL7048317 | 0.82 | NPC1 (0.51) | LOXLOXL2KDM4EMEN1KMT2A | |
| SCHEMBL5670014 | 0.81 | CETP (0.54) | LOXLOXL2CHRM5MEN1KMT2A | |
| SCHEMBL8074659 | 0.79 | MAPT (0.47) | LOXLOXL2F10KDM4EKMT2A | |
| SCHEMBL8773209 | 0.79 | MAPT (0.58) | L3MBTL1LMNAKDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691277-A | REACTING A 2,6-DIHALOGENOPYRIDINE WITH A META SUBSTITUTED PHENOL | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0692474-B1 | 2- (unsubstituted or substituted) (benzyloxy or phenoxy)-4-substituted-6-(meta-substituted phenoxy) pyridine, process for producing the same, and herbicidal composition | KUREHA CHEMICAL IND CO LTD (JP) | 1997-10-29 | — | — | EP | disclosed |
| EP-0692474-A1 | 2- (unsubstituted or substituted) (benzyloxy or phenoxy)-4-substituted-6-(meta-substituted phenoxy) pyridine, process for producing the same, and herbicidal composition | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-01-17 | — | — | EP | disclosed |