Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.57 |
| ▸ | HTR2B | P41595 | 3/20 | 0.57 |
| ▸ | CTSC | P53634 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL10518928 | 1.00 | HTR2C (0.57) | HTR2CHTR2BCTSCHTTMEN1 | |
| SCHEMBL8773302 | 0.94 | HTR2C (0.63) | HTR2CHTR2BCTSCHTTMEN1 | |
| SCHEMBL8134913 | 0.94 | HTR2C (0.63) | HTR2CHTR2BCTSCHTTMEN1 | |
| SCHEMBL8134909 | 0.94 | HTR2C (0.63) | HTR2CHTR2BCTSCHTTMEN1 | |
| Trifluoroacetic Acid SCHEMBL28157725 | 0.83 | TSHR (0.55) | HTR2CHTR2BCTSCGLATSHR | |
| SCHEMBL31549533 | 0.83 | HTR2C (0.60) | HTR2CHTR2BCTSCHTTKDM4E | |
| Trifluoroacetic Acid SCHEMBL28626897 | 0.81 | PRCP (0.48) | HTR2CHTR2BKDM4EGID4TERT | |
| Trifluoroacetic Acid SCHEMBL5231460 | 0.80 | HTR2C (0.48) | HTR2CHTR2BCTSCKDM4ETERT | |
| Trifluoroacetic Acid SCHEMBL9037494 | 0.79 | GLA (0.53) | KMT2AL3MBTL1GLA | |
| SCHEMBL18875522 | 0.79 | HTR2C (0.56) | HTR2CHTR2BCTSCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674905-A | ADMINISTERING AS GASTRIN OR CHOLECYSTOKININ ANTAGONISTS | JAMES BLACK FOUNDATION LIMITED (GB) | 1997-10-07 | — | — | US | disclosed |
| EP-0655053-B1 | BICYCLOOCTANE AND BICYCLOHEPTANE DERIVATIVES | BLACK JAMES FOUNDATION (GB) | 1997-09-03 | — | — | EP | disclosed |
| EP-0655053-A1 | BICYCLOOCTANE AND BICYCLOHEPTANE DERIVATIVES. | BLACK JAMES FOUNDATION (GB) | 1995-05-31 | — | — | EP | disclosed |
| WO-1994000421-A1 | BICYCLOOCTANE AND BICYCLOHEPTANE DERIVATIVES | JAMES BLACK FOUNDATION LIMITED (GB) | 1994-01-06 | — | — | WO | disclosed |