Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | HTR5A | P47898 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038558 | 0.92 | GLA (0.60) | GLAPOLBALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL9060376 | 0.89 | GLA (0.59) | GLAPOLBALDH1A1MAPK1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL28157725 | 0.80 | TSHR (0.55) | GLAKDM1A | |
| SCHEMBL11063204 | 0.80 | GLA (0.48) | GLAPOLBALDH1A1MAPK1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL10724195 | 0.79 | KCNN4 (0.39) | POLBHTR5A | |
| Trifluoroacetic Acid SCHEMBL8773300 | 0.79 | HTR2C (0.57) | GLAL3MBTL1KMT2A | |
| Trifluoroacetic Acid SCHEMBL10518928 | 0.79 | HTR2C (0.57) | GLAL3MBTL1KMT2A | |
| SCHEMBL28869016 | 0.76 | GLA (0.53) | GLAALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL3393626 | 0.76 | GLA (0.62) | GLAALDH1A1MAPK1L3MBTL1LTA4H | |
| Trifluoroacetic Acid SCHEMBL29447618 | 0.76 | TSHR (0.52) | GLAALDH1A1MAPK1L3MBTL1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491943-A4 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RORER INT HOLDINGS (US) | 1996-02-14 | — | — | EP | disclosed |
| EP-0491943-A1 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-07-01 | — | — | EP | disclosed |
| WO-1992000295-A1 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-01-09 | — | — | WO | disclosed |