Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 18/20 | 0.55 |
| ▸ | HTR1A | P08908 | 16/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6115017 | 0.90 | SLC6A4 (0.52) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL8773516 | 0.86 | SLC6A4 (0.65) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL1344469 | 0.84 | SLC6A4 (0.65) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL8773508 | 0.81 | SLC6A4 (0.82) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL8837960 | 0.80 | SLC6A4 (0.59) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL9943151 | 0.78 | SLC6A4 (0.72) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL27892028 | 0.76 | SLC6A4 (0.60) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL8773500 | 0.75 | HTR1A (0.88) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL6115087 | 0.75 | HTR1A (0.49) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL8773592 | 0.74 | SLC6A4 (0.47) | SLC6A4HTR1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778970-B2 | Benzyl piperidine compound | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2014-07-15 | — | — | US | disclosed |
| US-8778970-B2 | Benzyl piperidine compound | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2014-07-15 | — | — | US | disclosed |
| US-20120130077-A1 | BENZYL PIPERIDINE COMPOUND | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130077-A1 | BENZYL PIPERIDINE COMPOUND | HTR1D, HTR1A, HTR1B | SLC6A4 23/4885HTR1A 2/4885CYP2D6 620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.