Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 10/20 | 0.43 |
| ▸ | RXRB | P28702 | 7/20 | 0.43 |
| ▸ | RXRG | P48443 | 5/20 | 0.43 |
| ▸ | RARB | P10826 | 12/20 | 0.43 |
| ▸ | RARG | P13631 | 11/20 | 0.43 |
| ▸ | RARA | P10276 | 9/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773715 | 1.00 | RXRA (0.43) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7884592 | 0.81 | RXRA (0.48) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8773712 | 0.81 | RXRA (0.42) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7884577 | 0.81 | RXRA (0.48) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7884579 | 0.81 | RXRA (0.48) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8773652 | 0.81 | RXRA (0.42) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7884588 | 0.81 | RXRA (0.48) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8773649 | 0.81 | RXRA (0.42) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8773711 | 0.81 | RXRA (0.42) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7881502 | 0.81 | RXRA (0.44) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728739-B1 | Biaromatic amide derivatives, pharmaceutical and cosmetic compositions containing them and their utilisations | CIRD GALDERMA (FR) | 1997-11-05 | — | — | EP | disclosed |
| EP-0728739-A1 | Biaromatic amide derivatives, pharmaceutical and cosmetic compositions containing them and their utilisations | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1996-08-28 | — | — | EP | disclosed |