SCHEMBL8773656

SCHEMBL8773656

CC(C)(C)N(NC(=O)c1ccc(I)cc1)C(=O)c1ccccc1

nearest known ligand 0.82

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.82
CYP3A4 P08684 1/20 0.71
CYP2C9 P11712 1/20 0.71
HPGD P15428 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10718820 1.00 POLB (0.82) POLBCYP3A4CYP2C9HPGDSMN1; SMN2
Rh-5849 SCHEMBL1538531 0.91 POLB (1.00) POLBCYP3A4CYP2C9HPGDSMN1; SMN2
SCHEMBL8167374 0.88 POLB (0.88) POLBCYP3A4CYP2C9HPGDSMN1; SMN2
SCHEMBL9826327 0.87 POLB (0.85) POLBCYP3A4CYP2C9HPGDSMN1; SMN2
SCHEMBL9825457 0.87 POLB (0.85) POLBCYP3A4CYP2C9HPGDSMN1; SMN2
SCHEMBL8773665 0.87 POLB (0.85) POLBCYP3A4CYP2C9HPGDSMN1; SMN2
SCHEMBL9877264 0.87 POLB (0.85) POLBCYP3A4CYP2C9HPGDSMN1; SMN2
SCHEMBL9714073 0.87 POLB (0.85) POLBCYP3A4CYP2C9HPGDSMN1; SMN2
SCHEMBL9714077 0.87 POLB (0.85) POLBCYP3A4CYP2C9HPGDSMN1; SMN2
SCHEMBL9496264 0.87 POLB (0.85) POLBCYP3A4CYP2C9HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0630568-B1 Method of controlling insects ROHM & HAAS (US) 1997-09-10 EP claimed
EP-0630568-A1 Method of controlling insects ROHM AND HAAS COMPANY (US) 1994-12-28 EP claimed
US-5358966-A Using n,n'-diacylhydrazine ROHM AND HAAS COMPANY (US) 1994-10-25 US claimed
EP-0630568-B1 Method of controlling insects ROHM & HAAS (US) 1997-09-10 EP disclosed
EP-0630568-A1 Method of controlling insects ROHM AND HAAS COMPANY (US) 1994-12-28 EP disclosed
US-5358966-A Using n,n'-diacylhydrazine ROHM AND HAAS COMPANY (US) 1994-10-25 US disclosed