Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 20/20 | 0.78 |
| ▸ | SLC6A4 | P31645 | 20/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162833 | 0.93 | HTR1A (0.77) | HTR1ASLC6A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL1162429 | 0.92 | HTR1A (0.76) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL15871253 | 0.90 | HTR1A (0.73) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL11949164 | 0.89 | HTR1A (0.86) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL1344845 | 0.89 | HTR1A (0.83) | HTR1ASLC6A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL1345132 | 0.88 | HTR1A (0.82) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL1344325 | 0.88 | HTR1A (1.00) | HTR1ASLC6A4CYP2D6 | |
| Bromide SCHEMBL1347120 | 0.87 | HTR1A (0.98) | HTR1ASLC6A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL1345892 | 0.87 | HTR1A (0.98) | HTR1ASLC6A4CYP2D6 | |
| Fumaric Acid SCHEMBL1347514 | 0.86 | HTR1A (0.88) | HTR1ASLC6A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778970-B2 | Benzyl piperidine compound | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2014-07-15 | — | — | US | disclosed |
| US-20120130077-A1 | BENZYL PIPERIDINE COMPOUND | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130077-A1 | BENZYL PIPERIDINE COMPOUND | HTR1D, HTR1A, HTR1B | HTR1A 2/4885SLC6A4 23/4885CYP2D6 620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.