SCHEMBL8773863

SCHEMBL8773863

CCCCO[Zr](I)(I)(I)OCCCC

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
TSHR P16473 5/20 0.36
CYP3A4 P08684 4/20 0.36
ALDH1A1 P00352 2/20 0.35
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
LMNA P02545 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
ATM Q13315 1/20 0.32
THRB P10828 1/20 0.32
CYP2D6 P10635 2/20 0.31
CYP1A2 P05177 1/20 0.31
HPGD P15428 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11852770 0.71 ADRB2 (0.41) ADRB2ADRB1ADRB3SMN1; SMN2TSHR
SCHEMBL310148 0.69 ADRB2 (0.45) ADRB2ADRB1ADRB3SMN1; SMN2TSHR
Hydrochloric Acid SCHEMBL6435366 0.69
Hydrochloric Acid SCHEMBL9709345 0.67 ADRB2 (0.43) ADRB2ADRB1ADRB3SMN1; SMN2TSHR
Hydrochloric Acid SCHEMBL31501831 0.67 ADRB2 (0.43) ADRB2ADRB1ADRB3SMN1; SMN2TSHR
Fluoride SCHEMBL27823338 0.67 ADRB2 (0.43) ADRB2ADRB1ADRB3SMN1; SMN2TSHR
Hydrochloric Acid SCHEMBL10495326 0.65 TSHR (0.63) ADRB2ADRB1ADRB3SMN1; SMN2TSHR
Hydrochloric Acid SCHEMBL12501118 0.65 TSHR (0.63) ADRB2ADRB1ADRB3SMN1; SMN2TSHR
Hydrochloric Acid SCHEMBL28489956 0.65 TSHR (0.63) ADRB2ADRB1ADRB3SMN1; SMN2TSHR
SCHEMBL30317672 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714920-B1 Catalyst for polymerization of olefins NIPPON OIL CO LTD (JP) 1997-11-05 EP disclosed
EP-0714920-A1 Catalyst for polymerization of olefins NIPPON OIL CO. LTD. (JP) 1996-06-05 EP disclosed