Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726925 | 0.86 | HDAC1 (0.42) | ALDH1A1KCNJ11HDAC1HDAC6MEN1 | |
| SCHEMBL8528629 | 0.83 | AKR1C3 (0.52) | ALDH1A1AKR1C2AKR1C1AKR1C3AKR1C4 | |
| SCHEMBL25096707 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KCNJ11HDAC1HDAC6MEN1 | |
| SCHEMBL3576620 | 0.80 | KDM4E (0.53) | ALDH1A1AKR1C2AKR1C1AKR1C3AKR1C4 | |
| SCHEMBL3991288 | 0.80 | ALDH1A1 (0.37) | ALDH1A1AKR1C2AKR1C1AKR1C3AKR1C4 | |
| SCHEMBL4289283 | 0.79 | LCK (0.40) | AKR1C2AKR1C1AKR1C3AKR1C4HSD17B10 | |
| SCHEMBL30124621 | 0.78 | KMT2A (0.41) | ALDH1A1KCNJ11HDAC1HDAC6MEN1 | |
| SCHEMBL8773844 | 0.78 | KMT2A (0.41) | ALDH1A1KCNJ11HDAC1HDAC6MEN1 | |
| SCHEMBL18398288 | 0.77 | KCNJ11 (0.37) | ALDH1A1HSD17B10KCNJ11HDAC1HDAC6 | |
| SCHEMBL28091550 | 0.76 | KDM4E (0.40) | HSD17B10MAP2K1KDM4EHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470669-B1 | Preparation of fluorophenols, fluorohalophenols, N-acylfluoroanilines, and N-acylfluorohaloanilines | DOWELANCO (US) | 1997-11-12 | — | — | EP | disclosed |
| US-5164502-A | Fluorinating agents | DOWELANCO (US) | 1992-11-17 | — | — | US | disclosed |
| US-5116982-A | Fluorination | DOWELANCO (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0470669-A2 | Preparation of fluorophenols, fluorohalophenols, N-acylfluoroanilines, and N-acylfluorohaloanilines | DOWELANCO (US) | 1992-02-12 | — | — | EP | disclosed |