SCHEMBL8773903

SCHEMBL8773903

CC(C)(C)[C@H](NC(=O)C(CCc1ccccc1)CC(=O)O)C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 20/20 0.72
MMP3 P08254 9/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7763178 0.81 MMP2 (0.74) MMP2MMP3
SCHEMBL7108593 0.81 MMP2 (0.64) MMP2MMP3
SCHEMBL7108595 0.79 MMP2 (0.55) MMP2MMP3
SCHEMBL7108591 0.78 MMP2 (0.76) MMP2MMP3
SCHEMBL7051257 0.77 MMP2 (0.49) MMP2MMP3
SCHEMBL7114635 0.77 MMP2 (0.53) MMP2MMP3
SCHEMBL10734883 0.76 CPA1 (0.67) MMP2
SCHEMBL11311301 0.76 CPA1 (0.67) MMP2
SCHEMBL9196227 0.76 CPA1 (0.67) MMP2
SCHEMBL24024089 0.76 MMP2 (0.51) MMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0793643-A1 MATRIX METALLOPROTEASE INHIBITORS SYNTEX (U.S.A.) INC. (US) 1997-09-10 EP disclosed
WO-1996016027-A1 MATRIX METALLOPROTEASE INHIBITORS SYNTEX (U.S.A.) INC. (US) 1996-05-30 WO disclosed