Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | RAD52 | P43351 | 2/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14589612 | 1.00 | HTT (0.58) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL8586568 | 1.00 | HTT (0.58) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL8439979 | 1.00 | HTT (0.58) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL901713 | 1.00 | HTT (0.58) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL9917199 | 1.00 | HTT (0.58) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL8438524 | 1.00 | HTT (0.58) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL308046 | 1.00 | HTT (0.58) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL1537860 | 1.00 | HTT (0.58) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL308688 | 1.00 | HTT (0.58) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL14589610 | 1.00 | HTT (0.58) | HTTDNM1KMT2AHSP90AA1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793517-A1 | COMPOSITION AND METHOD FOR ENHANCING ELECTROTRANSPORT AGENT DELIVERY | ALZA CORPORATION (US) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996015826-A1 | COMPOSITION AND METHOD FOR ENHANCING ELECTROTRANSPORT AGENT DELIVERY | ALZA CORPORATION (US) | 1996-05-30 | — | — | WO | disclosed |