Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 12/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925787 | 0.88 | PARP1 (0.54) | BRD4PARP1 | |
| SCHEMBL13088615 | 0.82 | ALDH1A1 (0.61) | — | |
| SCHEMBL10647684 | 0.82 | HDAC1 (0.49) | PARP1 | |
| SCHEMBL12017406 | 0.81 | PARP1 (0.34) | PARP1 | |
| SCHEMBL3044326 | 0.81 | IDH1 (0.46) | BRD4PARP1 | |
| SCHEMBL8824659 | 0.81 | PARP1 (0.41) | BRD4PARP1CSNK2A1ROCK2ROCK1 | |
| SCHEMBL10651705 | 0.80 | HDAC1 (0.53) | PARP1 | |
| SCHEMBL13088639 | 0.78 | CNR2 (0.52) | PARP1 | |
| SCHEMBL13088593 | 0.78 | KMT2A (0.50) | — | |
| SCHEMBL13088653 | 0.76 | SCN10A (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
| CN-1074216-A | Urea derivative | GLAXO GROUP LTD (GB) | 1993-07-14 | — | — | CN | disclosed |