Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 9/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | CCKAR | P32238 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BDKRB2 | P30411 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774572 | 0.81 | CCKBR (0.48) | CCKBRCCKAR | |
| SCHEMBL8774581 | 0.81 | CCKBR (0.48) | CCKBRCCKAR | |
| SCHEMBL8534606 | 0.79 | DRD4 (0.42) | CCKBRDRD4DRD2MAOBCCKAR | |
| SCHEMBL8534607 | 0.79 | DRD4 (0.42) | CCKBRDRD4DRD2MAOBCCKAR | |
| SCHEMBL9056441 | 0.79 | CCKBR (0.63) | CCKBRCCKARMAPT | |
| SCHEMBL8533535 | 0.79 | CCKBR (0.63) | CCKBRCCKARMAPT | |
| SCHEMBL8774381 | 0.78 | CCKBR (0.54) | CCKBRCCKARMAPT | |
| SCHEMBL8774318 | 0.78 | CCKBR (0.40) | CCKBRCCKAR | |
| SCHEMBL8774308 | 0.78 | CCKBR (0.40) | CCKBRCCKAR | |
| SCHEMBL8537694 | 0.76 | DRD4 (0.40) | CCKBRDRD4DRD2MAOBCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |