Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 6/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774144 | 1.00 | THRA (0.44) | THRATHRBPTPN11PTPN1PTPN6 | |
| SCHEMBL8773975 | 1.00 | THRA (0.44) | THRATHRBPTPN11PTPN1PTPN6 | |
| SCHEMBL8773991 | 0.98 | THRA (0.44) | THRATHRBPTPN11PTPN1PTPN6 | |
| SCHEMBL8774167 | 0.98 | THRA (0.44) | THRATHRBPTPN11PTPN1PTPN6 | |
| SCHEMBL8774112 | 0.98 | THRA (0.44) | THRATHRBPTPN11PTPN1PTPN6 | |
| SCHEMBL8774164 | 0.98 | THRA (0.44) | THRATHRBPTPN11PTPN1PTPN6 | |
| SCHEMBL8774160 | 0.98 | THRA (0.44) | THRATHRBPTPN11PTPN1PTPN6 | |
| SCHEMBL8773974 | 0.98 | THRA (0.44) | THRATHRBPTPN11PTPN1PTPN6 | |
| SCHEMBL8774005 | 0.98 | THRA (0.44) | THRATHRBPTPN11PTPN1PTPN6 | |
| SCHEMBL8774098 | 0.93 | THRA (0.45) | THRATHRBPTPN11PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496896-B1 | CYCLOBUTANECARBOXYLIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | KANTO KAGAKU (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5545747-A | STABLE FERROELECTRIC LIQUID CRYSTALLINE COMPOUNDS | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1996-08-13 | — | — | US | disclosed |
| EP-0496896-A1 | CYCLOBUTANECARBOXYLIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1992-08-05 | — | — | EP | disclosed |