Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774388 | 0.93 | PNMT (0.45) | PNMTNPC1RAB9ASIGMAR1HTR2A | |
| SCHEMBL8774021 | 0.85 | PNMT (0.46) | PNMTNPC1RAB9AHTR2ADRD2 | |
| SCHEMBL8774252 | 0.81 | PNMT (0.47) | PNMTNPC1RAB9AHTR2ADRD2 | |
| Hydrochloric Acid SCHEMBL3385861 | 0.79 | PNMT (0.52) | PNMTNPC1RAB9AHTR2ADRD2 | |
| Bromide SCHEMBL3383744 | 0.79 | PNMT (0.52) | PNMTNPC1RAB9AHTR2ADRD2 | |
| Hydrochloric Acid SCHEMBL30274953 | 0.79 | PNMT (0.52) | PNMTNPC1RAB9AHTR2ADRD2 | |
| Fluoride Ion SCHEMBL3384402 | 0.79 | PNMT (0.52) | PNMTNPC1RAB9AHTR2ADRD2 | |
| Iodide SCHEMBL3382482 | 0.79 | PNMT (0.52) | PNMTNPC1RAB9AHTR2ADRD2 | |
| Hydrochloric Acid SCHEMBL8159750 | 0.74 | PNMT (0.44) | PNMTNPC1RAB9AHTR2ADRD2 | |
| Hexane SCHEMBL8572947 | 0.71 | PNMT (0.47) | PNMTNPC1RAB9ASIGMAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476671-B1 | Homogeneous catalysts for olefin polymerization | DOW CHEMICAL CO (US) | 1997-11-05 | — | — | EP | disclosed |
| EP-0745617-A2 | Olefin polymerisation process | THE DOW CHEMICAL COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |
| US-5312938-A | Complexing an aminotitanium compound with an indene compound | THE DOW CHEMICAL COMPANY (US) | 1994-05-17 | — | — | US | disclosed |
| US-5194532-A | Complexes of titanium, indene derivatives and secondary amines | THE DOW CHEMICAL COMPANY (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0476671-A2 | Homogeneous catalysts and olefin polymerization process | THE DOW CHEMICAL COMPANY (US) | 1992-03-25 | — | — | EP | disclosed |