SCHEMBL8774261

SCHEMBL8774261

O=C(Nc1ccc(Cl)cc1)NC1N=C(c2ccccc2F)c2ccccc2N(CC(=O)N2CC3CCC(CC3)C2)C1=O

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 20/20 0.77
CCKAR P32238 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8774267 1.00 CCKBR (0.77) CCKBRCCKAR
SCHEMBL9054824 0.94 CCKBR (0.84) CCKBRCCKAR
SCHEMBL9054828 0.94 CCKBR (0.84) CCKBRCCKAR
SCHEMBL9057224 0.88 CCKBR (0.73) CCKBRCCKAR
SCHEMBL9057226 0.88 CCKBR (0.73) CCKBRCCKAR
SCHEMBL9054895 0.88 CCKBR (0.86) CCKBRCCKAR
SCHEMBL9054891 0.88 CCKBR (0.86) CCKBRCCKAR
SCHEMBL9058629 0.88 CCKBR (0.84) CCKBRCCKAR
SCHEMBL9057664 0.88 CCKBR (0.84) CCKBR
SCHEMBL8775400 0.88 CCKBR (0.84) CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0804425-A2 BENZODIAZEPINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-11-05 EP disclosed
WO-1996004254-A2 BENZODIAZEPINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-02-15 WO disclosed