SCHEMBL8774265

SCHEMBL8774265

COC(=O)c1cccc(NC(=O)NC2N=C(c3ccccc3F)c3ccccc3NC2=O)c1

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 13/20 0.67
CCKAR P32238 7/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9866205 0.80 CCKBR (1.00) CCKBRCCKAR
SCHEMBL9866218 0.80 CCKBR (1.00) CCKBRCCKAR
SCHEMBL643406 0.78 CCKBR (0.79) CCKBRCCKAR
SCHEMBL7593098 0.77 CCKBR (1.00) CCKBRCCKAR
SCHEMBL9526643 0.77 CCKBR (1.00) CCKBRCCKAR
SCHEMBL643077 0.77 CCKBR (0.78) CCKBRCCKAR
SCHEMBL641958 0.76 CCKBR (1.00) CCKBRCCKAR
SCHEMBL9525828 0.76 CCKBR (1.00) CCKBRCCKAR
SCHEMBL9525817 0.76 CCKBR (1.00) CCKBRCCKAR
SCHEMBL9526420 0.75 CCKBR (0.78) CCKBRCCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0804425-A2 BENZODIAZEPINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-11-05 EP disclosed