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SCHEMBL8774357

SCHEMBL8774357

NC(=O)N(c1cccc(S(N)(=O)=O)c1)C1N=C(c2ccccc2F)c2ccccc2N(CC(=O)N2CC3CCC(CC3)C2)C1=O

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CCKBR P32239 19/20 0.52
▸ CCKAR P32238 5/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8774368 1.00 CCKBR (0.52) CCKBRCCKAR
SCHEMBL8774718 0.90 CCKBR (0.55) CCKBRCCKAR
SCHEMBL8774726 0.90 CCKBR (0.55) CCKBRCCKAR
SCHEMBL8775405 0.90 CCKBR (0.54) CCKBRCCKAR
SCHEMBL8779912 0.89 CCKBR (0.54) CCKBRCCKAR
SCHEMBL8774501 0.88 CCKBR (0.54) CCKBRCCKAR
SCHEMBL8774491 0.88 CCKBR (0.54) CCKBRCCKAR
SCHEMBL8774379 0.86 CCKBR (0.52) CCKBRCCKAR
SCHEMBL8774370 0.86 CCKBR (0.52) CCKBRCCKAR
SCHEMBL8773923 0.85 CCKBR (0.50) CCKBRCCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0804425-A2 BENZODIAZEPINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-11-05 — — EP disclosed