Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774302 | 0.99 | HSD17B10 (0.43) | FFAR1HSD17B10TSHRHTR2ARARB | |
| SCHEMBL8774909 | 0.96 | HSD17B10 (0.48) | FFAR1HSD17B10TSHRHTR2ARARB | |
| SCHEMBL8774821 | 0.96 | FFAR1 (0.43) | FFAR1HSD17B10TSHRHTR2ARARB | |
| SCHEMBL8774912 | 0.92 | TSHR (0.43) | FFAR1HSD17B10TSHRRARBRARA | |
| SCHEMBL8774295 | 0.90 | FFAR1 (0.44) | FFAR1CHRM2FFAR4 | |
| SCHEMBL8774475 | 0.88 | FFAR1 (0.40) | FFAR1HSD17B10TSHRHTR2ARARB | |
| SCHEMBL8774994 | 0.86 | FFAR1 (0.42) | FFAR1HSD17B10TSHRRARBRARA | |
| SCHEMBL8978919 | 0.86 | HSD17B10 (0.47) | FFAR1HSD17B10TSHRHTR2ARARB | |
| SCHEMBL8979108 | 0.84 | HSD17B10 (0.50) | FFAR1HSD17B10TSHRHTR2ARARB | |
| SCHEMBL8979042 | 0.84 | HSD17B10 (0.50) | FFAR1HSD17B10TSHRHTR2ARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0519370-A2 | Heterocyclic derivatives | MERCK PATENT GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |