SCHEMBL8774655

SCHEMBL8774655

C=CCN1C(=O)NC(OC)C1OC

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP3A4 P08684 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GLA P06280 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25767905 0.69 GAA (0.35)
SCHEMBL18106821 0.69 CYP3A4 (0.42) MAPTL3MBTL1CYP3A4MEN1KMT2A
SCHEMBL27796675 0.66 ALDH1A1 (0.34) ALDH1A1
SCHEMBL18106828 0.66 CYP3A4 (0.39) MAPTL3MBTL1CYP3A4MEN1KMT2A
SCHEMBL8774567 0.63 CYP3A4 (0.37) MAPTL3MBTL1CYP3A4MEN1KMT2A
SCHEMBL21844132 0.61 CYP3A4 (0.34) MAPTL3MBTL1CYP3A4
SCHEMBL18106814 0.61 CYP3A4 (0.34) MAPTL3MBTL1CYP3A4MEN1KMT2A
SCHEMBL21844127 0.61 CYP3A4 (0.34) MAPTL3MBTL1CYP3A4
SCHEMBL5133361 0.61 TDP1 (0.53) MAPTL3MBTL1CYP3A4MEN1KMT2A
SCHEMBL9055939 0.61 CYP3A4 (0.34) MAPTL3MBTL1CYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0629672-B1 Polymerizable imidazolidinones as wet adhesion promoters in aqueous paints NAT STARCH CHEM INVEST (US) 1997-11-12 EP claimed
EP-0629672-A2 Polymerizable imidazolidinones as wet adhesion promoters in aqueous paints National Starch and Chemical Investment Holding Corporation (US) 1994-12-21 EP claimed
EP-0629672-B1 Polymerizable imidazolidinones as wet adhesion promoters in aqueous paints NAT STARCH CHEM INVEST (US) 1997-11-12 EP disclosed
EP-0629672-A2 Polymerizable imidazolidinones as wet adhesion promoters in aqueous paints National Starch and Chemical Investment Holding Corporation (US) 1994-12-21 EP disclosed
EP-0124713-B1 POLYMERIZABLE IMIDAZOLIDINONES AND POLYMERS THEREOF USEFUL AS NONWOVEN BINDERS National Starch and Chemical Corporation (US) 1988-09-14 EP disclosed
US-4622374-A FORMALDEHYDE-FREE, SELF-CROSSLINKING NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1986-11-11 US disclosed
US-4596850-A Self-crosslinking; formaldehyde-free NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1986-06-24 US disclosed
US-4577031-A Polymerizable imidazolidinones NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1986-03-18 US disclosed
EP-0124713-A2 Polymerizable imidazolidinones and polymers thereof useful as nonwoven binders National Starch and Chemical Corporation (US) 1984-11-14 EP disclosed