Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | TLR4 | O00206 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | GRK6 | P43250 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774786 | 1.00 | KMT2A (0.33) | KMT2AMEN1RAB9AL3MBTL1CA2 | |
| SCHEMBL8774779 | 1.00 | KMT2A (0.33) | KMT2AMEN1RAB9AL3MBTL1CA2 | |
| SCHEMBL8774026 | 0.96 | KMT2A (0.35) | KMT2AMEN1RAB9AL3MBTL1CA2 | |
| SCHEMBL8774033 | 0.96 | KMT2A (0.35) | KMT2AMEN1RAB9AL3MBTL1CA2 | |
| SCHEMBL8775020 | 0.93 | MAPT (0.37) | KMT2AMEN1RAB9AL3MBTL1CA2 | |
| SCHEMBL8775011 | 0.93 | MAPT (0.37) | KMT2AMEN1RAB9AL3MBTL1CA2 | |
| SCHEMBL8775007 | 0.93 | MAPT (0.37) | KMT2AMEN1RAB9AL3MBTL1CA2 | |
| SCHEMBL8775027 | 0.92 | PKM (0.36) | KMT2AMEN1RAB9AL3MBTL1CA2 | |
| SCHEMBL8775023 | 0.92 | PKM (0.36) | KMT2AMEN1RAB9AL3MBTL1CA2 | |
| SCHEMBL8775022 | 0.92 | PKM (0.36) | KMT2AMEN1RAB9AL3MBTL1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0519370-A2 | Heterocyclic derivatives | MERCK PATENT GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |