Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774781 | 0.83 | TRPV3 (0.34) | TRPV3 | |
| SCHEMBL8774838 | 0.80 | OPRL1 (0.35) | — | |
| SCHEMBL8774787 | 0.78 | GAA (0.36) | — | |
| SCHEMBL8774738 | 0.77 | MAPT (0.38) | — | |
| SCHEMBL8774937 | 0.77 | TRPV3 (0.36) | TRPV3 | |
| SCHEMBL9162502 | 0.77 | ESR2 (0.33) | TRPV3ESR2 | |
| SCHEMBL9162511 | 0.77 | ESR2 (0.33) | TRPV3ESR2 | |
| SCHEMBL9162486 | 0.77 | ESR2 (0.33) | TRPV3ESR2 | |
| SCHEMBL8774929 | 0.77 | TRPV3 (0.36) | TRPV3 | |
| SCHEMBL9162495 | 0.77 | ESR2 (0.33) | TRPV3ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0519370-A2 | Heterocyclic derivatives | MERCK PATENT GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |