Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5551231 | 0.88 | NPC1 (0.53) | NPC1RAB9APTGS2GAAMAPT | |
| SCHEMBL5551227 | 0.88 | NPC1 (0.53) | NPC1RAB9APTGS2GAAMAPT | |
| SCHEMBL8774884 | 0.86 | NPC1 (0.51) | NPC1RAB9APTGS2GAAMAPT | |
| SCHEMBL5141674 | 0.85 | NPC1 (0.47) | NPC1RAB9APTGS2GAAMAPT | |
| SCHEMBL25422064 | 0.83 | NPC1 (0.45) | NPC1RAB9APTGS2GAAMAPT | |
| SCHEMBL2494333 | 0.77 | SIRT2 (0.57) | GAAMAPTTDP1NFE2L2SIRT2 | |
| SCHEMBL10128973 | 0.77 | HPGD (0.68) | NPC1RAB9APTGS2GAAMAPT | |
| SCHEMBL12700847 | 0.77 | HPGD (0.68) | NPC1RAB9APTGS2GAAMAPT | |
| SCHEMBL2498783 | 0.76 | SIRT2 (0.50) | PTGS2GAAMAPTTDP1HPGD | |
| SCHEMBL15900063 | 0.75 | GAA (0.44) | NPC1RAB9APTGS2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278757-B1 | Electroluminescent device with improved cathode | EASTMAN KODAK CO (US) | 1997-11-12 | — | — | EP | disclosed |
| EP-0281381-B1 | ELECTROLUMINESCENT DEVICE WITH MODIFIED THIN FILM LUMINESCENT ZONE | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1992-07-15 | — | — | EP | disclosed |
| EP-0349265-A2 | Electroluminescent devices | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1990-01-03 | — | — | EP | disclosed |