SCHEMBL8775008

SCHEMBL8775008

Cc1cccc(NC(=O)N[C@@H]2N=C(c3ccccc3F)c3ccccc3N(Cc3cc(C(C)(C)C)ccn3)C2=O)c1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 10/20 0.65
CCKAR P32238 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8534654 1.00 CCKBR (0.65) CCKBRCCKAR
SCHEMBL9057111 0.92 CCKBR (0.71) CCKBRCCKAR
SCHEMBL8538152 0.92 CCKBR (0.71) CCKBRCCKAR
SCHEMBL8534435 0.90 CCKBR (0.67) CCKBRCCKAR
SCHEMBL9057807 0.90 CCKBR (0.67) CCKBRCCKAR
SCHEMBL8538375 0.89 CCKBR (0.71) CCKBRCCKAR
SCHEMBL9054618 0.88 CCKBR (0.65) CCKBRCCKAR
SCHEMBL8586019 0.88 CCKBR (0.65) CCKBRCCKAR
SCHEMBL9120535 0.84 CCKBR (0.68) CCKBRCCKAR
SCHEMBL8534534 0.84 CCKBR (0.70) CCKBRCCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0804425-A2 BENZODIAZEPINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-11-05 EP disclosed
WO-1996004254-A2 BENZODIAZEPINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-02-15 WO disclosed