Biphenyl

Biphenyl

SCHEMBL8775063

CCCCCCCCOP(O)OCCCCCCCC.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45
RARB P10826 3/20 0.44
LTA4H P09960 1/20 0.43
SOAT1 P35610 1/20 0.43
CNR2 P34972 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPK1 P28482 1/20 0.42
PTPN1 P18031 1/20 0.42
FAAH O00519 6/20 0.41
NR5A1 Q13285 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL10591386 1.00 TSHR (0.45) TSHRALDH1A1LMNARARBLTA4H
Biphenyl SCHEMBL28236377 0.97 TSHR (0.42) TSHRALDH1A1LMNARARBLTA4H
Biphenyl SCHEMBL1548305 0.95 TSHR (0.41) TSHRALDH1A1LMNARARBLTA4H
Biphenyl SCHEMBL27870569 0.89 TSHR (0.45) TSHRALDH1A1LMNARARBLTA4H
Biphenyl SCHEMBL27623128 0.89 TSHR (0.45) TSHRALDH1A1LMNARARBLTA4H
Biphenyl SCHEMBL27870570 0.89 TSHR (0.45) TSHRALDH1A1LMNARARBLTA4H
Biphenyl SCHEMBL27752677 0.89 LTA4H (0.45) TSHRALDH1A1LMNARARBLTA4H
Benzene SCHEMBL28526211 0.89 GBA1 (0.42) TSHRALDH1A1LMNALTA4HTP53
Phenol SCHEMBL28773564 0.88 NR5A1 (0.51) TSHRALDH1A1LMNALTA4HTP53
SCHEMBL28538580 0.85 CETP (0.48) TSHRALDH1A1LMNALTA4HCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103992552-A Tear-resistant cable material ANHUI HUAHONG ELECTRIC SHARE CO LTD 2014-08-20 CN disclosed
EP-0646146-B1 IMPROVED PROCESS FOR PREPARING EXTENDED CHAIN POLYESTERS AND BLOCK OR GRAFT COPOLYESTERS ALLIED SIGNAL INC (US) 1997-11-12 EP disclosed
EP-0646146-A1 IMPROVED PROCESS FOR PREPARING EXTENDED CHAIN POLYESTERS AND BLOCK OR GRAFT COPOLYESTERS AlliedSignal Inc. (US) 1995-04-05 EP disclosed
US-5389721-A Using phosphorous(III)-containing chain extension reagents; heating; using no catalytic substances which contain elements from groups VA and VIA of the periodic table ALLIEDSIGNAL INC. (US) 1995-02-14 US disclosed
WO-1993025601-A1 IMPROVED PROCESS FOR PREPARING EXTENDED CHAIN POLYESTERS AND BLOCK OR GRAFT COPOLYESTERS ALLIED-SIGNAL INC. (US) 1993-12-23 WO disclosed