Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 7/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687967 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRPAOXUSP2DNM1 | |
| SCHEMBL8775415 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRPAOXUSP2DNM1 | |
| SCHEMBL6684829 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRPAOXUSP2DNM1 | |
| SCHEMBL6684833 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRPAOXUSP2DNM1 | |
| SCHEMBL6687965 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRPAOXUSP2DNM1 | |
| SCHEMBL3108917 | 0.98 | ALDH1A1 (0.37) | ALDH1A1TSHRPAOXUSP2HSD17B10 | |
| SCHEMBL3295908 | 0.98 | ALDH1A1 (0.37) | ALDH1A1TSHRPAOXUSP2HSD17B10 | |
| SCHEMBL36879 | 0.92 | USP2 (0.37) | ALDH1A1TSHRPAOXUSP2HSD17B10 | |
| SCHEMBL3670018 | 0.92 | USP2 (0.37) | ALDH1A1TSHRPAOXUSP2HSD17B10 | |
| SCHEMBL33998 | 0.92 | USP2 (0.37) | ALDH1A1TSHRPAOXUSP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606742-B1 | Bile acid sequestrant | ROHM & HAAS (US) | 1997-11-19 | — | — | EP | claimed |
| US-5451397-A | Crosslinked amino functional acrylic amide polymer, reducing blood cholesterol levels | ROHM AND HAAS COMPANY (US) | 1995-09-19 | — | — | US | claimed |
| EP-0606742-A1 | Bile acid sequestrant | ROHM AND HAAS COMPANY (US) | 1994-07-20 | — | — | EP | claimed |
| EP-0606742-B1 | Bile acid sequestrant | ROHM & HAAS (US) | 1997-11-19 | — | — | EP | disclosed |
| US-5451397-A | Crosslinked amino functional acrylic amide polymer, reducing blood cholesterol levels | ROHM AND HAAS COMPANY (US) | 1995-09-19 | — | — | US | disclosed |
| EP-0606742-A1 | Bile acid sequestrant | ROHM AND HAAS COMPANY (US) | 1994-07-20 | — | — | EP | disclosed |
| US-5300288-A | Acrylic amide polymers | ROHM AND HAAS COMPANY (US) | 1994-04-05 | — | — | US | disclosed |
| EP-0428970-B1 | Process for preparing aqueous solutions or suspensions of quaternization products of tertiary aminoalkylesters or tertiary aminoalkylamides of acrylic or methacrylic acid, for instance of dimethylaminoethyl-acrylate-methochloride | BASF AG (DE) | 1994-01-19 | — | — | EP | disclosed |
| EP-0459632-A1 | Composition and method for controlling cholesterol | ROHM AND HAAS COMPANY (US) | 1991-12-04 | — | — | EP | disclosed |
| EP-0428970-A1 | Process for preparing aqueous solutions or suspensions of quaternization products of tertiary aminoalkylesters or tertiary aminoalkylamides of acrylic or methacrylic acid, for instance of dimethylaminoethyl-acrylate-methochloride | BASF Aktiengesellschaft (DE) | 1991-05-29 | — | — | EP | disclosed |
| EP-0113038-B1 | PROCESS FOR PREPARING CONCENTRATED AQUEOUS SOLUTIONS OF QUATERNIZED PRODUCTS FROM TERTIARY AMINO ALKYL ESTERS OR AMIDES OF ACRYLIC OR METHACRYLIC ACIDS | BASF Aktiengesellschaft (DE) | 1986-09-10 | — | — | EP | disclosed |
| US-4520210-A | ALKYLATION IN WATER SOLUBLE KETONE THEN SEPARATION | BASF AKTIENGESELLSCHAFT (DE) | 1985-05-28 | — | — | US | disclosed |
| EP-0113038-A2 | Process for preparing concentrated aqueous solutions of quaternized products from tertiary amino alkyl esters or amides of acrylic or methacrylic acids | BASF Aktiengesellschaft (DE) | 1984-07-11 | — | — | EP | disclosed |