SCHEMBL8775272

SCHEMBL8775272

CC1(C)OC(=O)[C@H](CC(=O)Cl)O1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GLS O94925 1/20 0.46
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2280018 1.00 GLS (0.46) GLSBACE1
SCHEMBL8775286 1.00 GLS (0.46) GLSBACE1
SCHEMBL18218788 0.83 GLS (0.47) GLSBACE1
SCHEMBL200462 0.83 GLS (0.47) GLSBACE1
SCHEMBL18219056 0.83 GLS (0.47) GLSBACE1
SCHEMBL18914987 0.83 GLS (0.47) GLSBACE1
SCHEMBL473047 0.83 GLS (0.47) GLSBACE1
SCHEMBL1005092 0.83 GLS (0.47) GLSBACE1
SCHEMBL23296774 0.81 GLS (0.46) GLSBACE1
SCHEMBL183678 0.81 GLS (0.46) GLSBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012135669-A1 NITROGEN RING CONTAINING COMPOUNDS FOR TREATMENT OF INFLAMMATORY DISORDERS WEINGARTEN M DAVID (US) 2012-10-04 WO disclosed
EP-0804430-A1 SYNTHESIS OF OPTICALLY PURE 4-ALKENYL- OR 4-ALKANYL-2-HYDROXYTETRONIC ACIDS THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1997-11-05 EP disclosed
US-5656662-A TREATING OR PREVENTING ATHEROSCLEROTIC DISORDERS, INHIBITING INFLAMMATORY CYTOKINES THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1997-08-12 US disclosed
US-5504107-A ANTICOAGULANTS, PREVENTING ATHEROSCLEROSIS THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1996-04-02 US disclosed
WO-1995032194-A1 SYNTHESIS OF OPTICALLY PURE 4-ALKENYL- OR 4-ALKANYL-2-HYDROXYTETRONIC ACIDS THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1995-11-30 WO disclosed