SCHEMBL8775512

SCHEMBL8775512

COC1(N=C=O)C=CC(N=C=O)C=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11793966 0.62
SCHEMBL6388486 0.56
SCHEMBL11081298 0.55
SCHEMBL7509568 0.52
SCHEMBL19859474 0.51 ALDH1A1 (0.37)
SCHEMBL2521515 0.51
SCHEMBL420892 0.50
SCHEMBL4047571 0.49
SCHEMBL4044601 0.49 ALDH1A1 (0.50)
SCHEMBL4054600 0.49 ALDH1A1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0482682-B1 Method for the manufacture of flexible polyurethane foam RECTICEL (BE) 1997-11-19 EP disclosed
US-5194453-A Reducing density by mechanical frothing and expansion under reduced pressure RECTICEL (BE) 1993-03-16 US disclosed
EP-0482682-A1 Method for the manufacture of flexible polyurethane foam RECTICEL (BE) 1992-04-29 EP disclosed
US-4511682-A BLOCK POLYMERIZATION OF POLYMERIC POLYOL AND POLYMERIC ANHYDRIDE UNION CARBIDE CORPORATION (US) 1985-04-16 US disclosed
EP-0131804-A1 Water-dispersible coating compositions and process UNION CARBIDE CORPORATION (US) 1985-01-23 EP disclosed
WO-1985000174-A1 WATER-DISPERSIBLE COATING COMPOSITIONS AND PROCESS UNION CARBIDE CORPORATION (US) 1985-01-17 WO disclosed
US-4060439-A Polyurethane foam composition and method of making same UNION CARBIDE CORPORATION (US) 1977-11-29 US disclosed