Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 7/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28012567 | 0.81 | KCNA5 (0.49) | KCNA5KCNH2MEN1GAAKMT2A | |
| SCHEMBL15704684 | 0.81 | KCNA5 (0.49) | KCNA5KCNH2MEN1GAAKMT2A | |
| SCHEMBL15280655 | 0.79 | KCNA5 (0.47) | KCNA5KCNH2MEN1GAAKMT2A | |
| SCHEMBL28382973 | 0.78 | MEN1 (0.49) | KCNA5KCNH2MEN1GAAKMT2A | |
| SCHEMBL21742078 | 0.78 | KCNA5 (0.50) | KCNA5KCNH2MEN1GAAKMT2A | |
| SCHEMBL21742312 | 0.77 | KCNA5 (0.42) | KCNA5KCNH2MEN1GAAKMT2A | |
| SCHEMBL21742015 | 0.76 | KCNA5 (0.45) | KCNA5KCNH2MEN1GAAKMT2A | |
| SCHEMBL16440378 | 0.75 | SLC6A2 (0.52) | KCNA5KCNH2MEN1GAAKMT2A | |
| SCHEMBL21742017 | 0.75 | KCNH2 (0.44) | KCNA5KCNH2MEN1GAAKMT2A | |
| SCHEMBL21742316 | 0.75 | KCNA5 (0.44) | KCNA5KCNH2MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107027309-B | Antibacterial agent | 昆士兰大学 | 2021-10-01 | — | — | CN | disclosed |
| US-10947271-B2 | Antibacterial agents | THE UNIVERSITY OF QUEENSLAND (AU) | 2021-03-16 | — | — | US | disclosed |
| US-20170204138-A1 | ANTIBACTERIAL AGENTS | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-07-20 | — | — | US | disclosed |
| EP-3105244-A1 | ANTIBACTERIAL AGENTS | The University Of Queensland (AU) | 2016-12-21 | — | — | EP | disclosed |
| WO-2015117196-A1 | ANTIBACTERIAL AGENTS | THE UNIVERSITY OF QUEENSLAND (AU) | 2015-08-13 | — | — | WO | disclosed |
| EP-0807098-A1 | IMPROVED PROCESS FOR REDUCTIVE HYDROLYSIS OF NITRILES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996023753-A1 | IMPROVED PROCESS FOR REDUCTIVE HYDROLYSIS OF NITRILES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204138-A1 | ANTIBACTERIAL AGENTS | VNN1, ASNS, AAAS | KCNA5 1199/4885KCNH2 2500/4885MEN1 3291/4885 |
| US-10947271-B2 | Antibacterial agents | VNN1, ASNS, AAAS | KCNA5 1199/4885KCNH2 2500/4885MEN1 3291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.