Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.43 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | CPB1 | P15086 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5087420 | 1.00 | GABRR1 (0.43) | GABRR1GGT1PAOXCPB2TP53 | |
| Acetic Acid SCHEMBL10524376 | 0.98 | GABRR1 (0.41) | GABRR1GGT1PAOXCPB2TP53 | |
| Acetic Acid SCHEMBL29012712 | 0.98 | GABRR1 (0.41) | GABRR1GGT1PAOXCPB2TP53 | |
| Acetic Acid SCHEMBL29259484 | 0.96 | GABRR1 (0.40) | GABRR1GGT1PAOXCPB2CPB1 | |
| Carbamic Acid SCHEMBL28243838 | 0.91 | GABRR1 (0.43) | GABRR1GGT1PAOXCPB2TP53 | |
| Acetic Acid SCHEMBL8775556 | 0.89 | GABRR1 (0.35) | GABRR1GGT1CPB2 | |
| SCHEMBL27099 | 0.88 | — | — | |
| Acetic Acid SCHEMBL28385152 | 0.87 | CA1 (0.38) | GABRR1GGT1PAOXCPB2 | |
| SCHEMBL28852761 | 0.85 | — | — | |
| Acetic Acid SCHEMBL3841808 | 0.85 | FFAR3 (0.39) | TP53FFAR3LCKFYNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101146905-B | Anti-corrosion detergent compositions and use of same in cleaning dental and medical instruments | SCICAN | 2011-04-06 | — | — | CN | claimed |
| CN-101146905-A | Anti-corrosion detergent compositions and use of same in cleaning dental and medical instruments | SCICAN (CA) | 2008-03-19 | — | — | CN | claimed |
| EP-0616979-B1 | Method for solubilizing silica | ROHM & HAAS (US) | 1997-11-19 | — | — | EP | claimed |
| US-11072546-B2 | Decomplexation of chelated hardness at high pH | CONOCOPHILLIPS COMPANY (US) | 2021-07-27 | — | — | US | disclosed |
| US-20190300401-A1 | DECOMPLEXATION OF CHELATED HARDNESS AT HIGH PH | CONOCOPHILLIPS COMPANY | 2019-10-03 | — | — | US | disclosed |
| CN-103266029-A | Enhanced activity biocidal hyrogen peroxide composition | ASEPTIX TECHNOLOGIES B V | 2013-08-28 | — | — | CN | disclosed |
| CN-101484564-B | Skin friendly broad spectrum disinfecting compositions | CENTENNIAL VENTURES B V | 2011-08-03 | — | — | CN | disclosed |
| CN-101146905-B | Anti-corrosion detergent compositions and use of same in cleaning dental and medical instruments | SCICAN | 2011-04-06 | — | — | CN | disclosed |
| CN-101484564-A | Skin friendly broad spectrum disinfecting compositions | CENTENNIAL VENTURES B V (NL) | 2009-07-15 | — | — | CN | disclosed |
| CN-101374936-A | Biocidal hydrogen peroxide compositions with enhanced activity | ASEPTIX RES B V (NL) | 2009-02-25 | — | — | CN | disclosed |
| CN-101146905-A | Anti-corrosion detergent compositions and use of same in cleaning dental and medical instruments | SCICAN (CA) | 2008-03-19 | — | — | CN | disclosed |