Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.30 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8168093 | 0.94 | SLC6A4 (0.34) | SLC6A4SLC6A3GPR3SLC22A2SLC22A3 | |
| SCHEMBL6469961 | 0.92 | CHRM3 (0.34) | SLC6A4SLC6A3GPR3SLC22A2SLC22A3 | |
| SCHEMBL8776108 | 0.87 | SLC6A4 (0.40) | SLC6A4SLC6A3GPR3MEN1POLB | |
| SCHEMBL8501697 | 0.86 | SLC6A4 (0.33) | SLC6A4SLC6A3GPR3 | |
| SCHEMBL7573529 | 0.81 | TDP2 (0.32) | MEN1KMT2AATM | |
| SCHEMBL7581453 | 0.76 | NPC1 (0.30) | — | |
| SCHEMBL7571804 | 0.76 | — | — | |
| SCHEMBL7580510 | 0.76 | NPC1 (0.30) | — | |
| SCHEMBL7575276 | 0.76 | CHRM3 (0.33) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7571273 | 0.76 | NR1I2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528041-B1 | NOVEL TRANSITION METAL COMPOUND AND PROCESS FOR POLYMERIZING OLEFIN BY USING THE SAME | MITSUI TOATSU CHEMICALS (JP) | 1997-11-19 | — | — | EP | disclosed |
| US-5439994-A | Preparing polymers with wide molecular weight distribution | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5359102-A | Having cyclopentadienyl, indenyl, dicyclopentadienyl, and or fluorenyl group or theier derivatives as a legand used together with cocatalyst aluminoxane | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-10-25 | — | — | US | disclosed |
| EP-0528041-A1 | NOVEL TRANSITION METAL COMPOUND AND PROCESS FOR POLYMERIZING OLEFIN BY USING THE SAME | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-02-24 | — | — | EP | disclosed |