Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 8/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8776013 | 0.99 | TBXAS1 (0.56) | TBXAS1EPHX2CYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL8776082 | 0.95 | TBXAS1 (0.54) | TBXAS1EPHX2CYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL8776110 | 0.85 | TBXAS1 (0.56) | TBXAS1EPHX2CYP2C9CYP2C19TBXA2R | |
| SCHEMBL8775884 | 0.82 | TBXAS1 (0.64) | TBXAS1EPHX2CYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL8775863 | 0.82 | TBXAS1 (0.64) | TBXAS1EPHX2CYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL8776095 | 0.82 | TBXAS1 (0.64) | TBXAS1EPHX2CYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL8775780 | 0.82 | TBXAS1 (0.64) | TBXAS1EPHX2CYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL8775881 | 0.82 | TBXAS1 (0.54) | TBXAS1EPHX2CYP2C9CYP2C19LMNA | |
| SCHEMBL8775891 | 0.81 | TBXAS1 (0.62) | TBXAS1EPHX2CYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL8775855 | 0.81 | TBXAS1 (0.54) | TBXAS1EPHX2CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |