Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775938 | 0.88 | PNMT (0.38) | PNMTNPC1RAB9APGRHTR7 | |
| SCHEMBL3373312 | 0.86 | PNMT (0.36) | PNMTNPC1RAB9APGRHTR7 | |
| SCHEMBL6469960 | 0.85 | PNMT (0.35) | PNMTNPC1RAB9APGRHTR7 | |
| SCHEMBL8998590 | 0.85 | PNMT (0.35) | PNMTNPC1RAB9APGRHTR7 | |
| Hydrochloric Acid SCHEMBL6557621 | 0.84 | PNMT (0.35) | PNMTNPC1RAB9APGRDRD2 | |
| Hydrochloric Acid SCHEMBL8537424 | 0.73 | — | — | |
| SCHEMBL31077577 | 0.72 | PNMT (0.46) | PNMTNPC1RAB9APGRHTR7 | |
| SCHEMBL27348144 | 0.68 | PNMT (0.45) | PNMTNPC1RAB9APGRHTR7 | |
| SCHEMBL28220071 | 0.67 | PNMT (0.44) | PNMTNPC1RAB9APGRHTR7 | |
| SCHEMBL28286932 | 0.67 | PNMT (0.44) | PNMTNPC1RAB9APGRHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528041-B1 | NOVEL TRANSITION METAL COMPOUND AND PROCESS FOR POLYMERIZING OLEFIN BY USING THE SAME | MITSUI TOATSU CHEMICALS (JP) | 1997-11-19 | — | — | EP | disclosed |
| US-5439994-A | Preparing polymers with wide molecular weight distribution | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5359102-A | Having cyclopentadienyl, indenyl, dicyclopentadienyl, and or fluorenyl group or theier derivatives as a legand used together with cocatalyst aluminoxane | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-10-25 | — | — | US | disclosed |
| EP-0528041-A1 | NOVEL TRANSITION METAL COMPOUND AND PROCESS FOR POLYMERIZING OLEFIN BY USING THE SAME | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-02-24 | — | — | EP | disclosed |