Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.34 |
| ▸ | RARA | P10276 | 4/20 | 0.34 |
| ▸ | RARB | P10826 | 4/20 | 0.34 |
| ▸ | RARG | P13631 | 4/20 | 0.34 |
| ▸ | APP | P05067 | 3/20 | 0.34 |
| ▸ | SNCA | P37840 | 3/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | RXRG | P48443 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11417197 | 0.86 | MAPT (0.85) | MAPTALOX15ALDH1A1PTGS1LMNA | |
| SCHEMBL11423435 | 0.85 | MAPT (0.60) | MAPTALOX15ALDH1A1PTGS1LMNA | |
| SCHEMBL9840299 | 0.79 | MAPT (0.51) | MAPTALOX15ALDH1A1PTGS1LMNA | |
| SCHEMBL9840296 | 0.79 | MAPT (0.51) | MAPTALOX15ALDH1A1PTGS1LMNA | |
| SCHEMBL5437068 | 0.79 | ALDH1A1 (0.58) | MAPTALOX15ALDH1A1PTGS1LMNA | |
| SCHEMBL8390312 | 0.76 | MAPT (0.67) | MAPTALOX15ALDH1A1PTGS1LMNA | |
| SCHEMBL8390315 | 0.76 | MAPT (0.67) | MAPTALOX15ALDH1A1PTGS1LMNA | |
| Canthaxanthin SCHEMBL12920083 | 0.76 | MAPT (1.00) | MAPTALOX15ALDH1A1PTGS1LMNA | |
| Canthaxanthin SCHEMBL8971840 | 0.76 | MAPT (1.00) | MAPTALOX15ALDH1A1PTGS1LMNA | |
| Canthaxanthin SCHEMBL19618 | 0.76 | MAPT (1.00) | MAPTALOX15ALDH1A1PTGS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808159-A1 | USE OR RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) | WARNER-LAMBERT COMPANY (US) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024344-A1 | USE OF RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) | WARNER-LAMBERT COMPANY (US) | 1996-08-15 | — | — | WO | disclosed |