Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL836356 | 0.84 | CA1 (0.52) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL5696622 | 0.83 | SLC6A2 (0.44) | MAPTCA1CA2SLC6A2SLC6A4 | |
| SCHEMBL27520267 | 0.82 | CA1 (0.53) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL5696485 | 0.81 | SLC6A2 (0.43) | MAPTCA1CA2SLC6A2SLC6A3 | |
| SCHEMBL5026930 | 0.81 | PGR (0.47) | MAPTTDP1SLC6A2SLC6A3MEN1 | |
| SCHEMBL14893388 | 0.79 | MAPT (0.50) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL2981658 | 0.78 | CA1 (0.57) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL2237898 | 0.78 | MAPT (0.45) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL1147059 | 0.77 | CA1 (0.55) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL4936697 | 0.77 | SLC6A2 (0.57) | MAPTCA1CA2TDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799202-A1 | PIPERAZINE DERIVATIVES, MEDICAMENTS CONTAINING THE SAME, THEIR USE AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1997-10-08 | — | — | EP | disclosed |